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Strings should only be used if the player is planning on playing on Eb tuning or lower. These are not to be fiddled with at all. Great for a very deep (almost baritone) sound for a guitar, but not something I would consider strumming.
So these strings are strings I use for my Ibanez. For a much heavier tone, and a much richer tone. If you want to drop-tune your guitar to anything, these are the strings to get. Because if you use a lighter gauge, the strings will get really f**ked up and the tension will be weird and it'll ultimately screw up your neck to the point where you would need a professional to fix it.