I tune to E standard & E flat with these strings, and they are wonderful. Only time they broke was when I threw my Strat across the room! Great strings, especially for the heavy-handed player!
They are really great strings for Punk Rock music, because of the thickness of them, pick sliding sounds really awesome. If you want strings that will sound great with power chords and pick sliding then skinny top and heavy bottom strings are the way to go. Solos also sound amazing due to the thickness. I am really happy using this strings and I don't want to use any others. I use them all the time in my punk rock band "Unwired Society"