He plays often this guitar, even if it's not his main guitar, you can see he plays with this guitar in many live songs.
According to the [Famous Martin Owners](http://www.martinguitar.com/players/famous-martin-owners.html) page on the C.F. Martin website, Kirk Hammett plays a D-42.
This guitar is a customized Peter Frampton version of a Martin D-42. It was customized by Martin luthier Dick Boak. It is strung with D'Addario or Elixir strings.
According to Martin's website, Isbell uses Martin D-42.
Seen here playing his 2003 Martin D-42 Dreadnought
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