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Are "high gain" 12ax7 preamp tubes worth it?

As the title suggests, are they worth it and do they have noticeable difference over "standard gain" 12ax7/ecc83 tubes?

GEAR:
  • Harley Benton TE-40 Deluxe
  • Bugera Vintage V22HD 22W Tube Guitar Amp Head
  • Epiphone Les Paul Custom Pro

It seems there are no "high gain" or "standard gain" 12AX7s. Just a different readiness to overdrive: https://www.thegearpage.net/board/index.php?threads/hi-gain-12ax7.2037070/

GEAR:
  • sE Electronics V7
  • Fender Vintage Series '57 Stratocaster
  • Blank slot