My best tour setups were very amp based. For straight ahead power trio rockin' i used the following as the finest incarnation of my fender/marshall rig:
Gibson lp standard, special and occasionally my strat
Radial tonebone aby w/tu2 on tuner out w/3rd switch set as a mute
Channel A to script logo mxr bluebox or vintage univox superfuzz set for gnarly octave fuzz w/low output for accent parts (rarely engaged), modified 2nd issue small stone, occassionly a mutron flanger annd sometimes a dm2, dm3 or carbon copy for slap into 63 fender showman normal channel input1 with 1st coupling cap value lowered to plexi bright input spec for less thump, trem channel disabled... settings vol 4, bright engaged, bass 3, treb 7 into whirlwind passive di feeding yamaha spx 90 for doubling effect with the speaker thru into a 1960tv cab with stock 90s uk greenbacks or 1960ax or bx
B channel to tonebender (vox, mk 2 or 3 or clone) or a silicon fuzzface set for lots of solo boost and low fuzz into a 100 watt marshall superlead cranked for good rhythm crunch (volume settings and channel used depends on the amp, i used a couple, all different but my main one had normal channel voicing tweaks and a bright cap mod), hot plate at -4dB attenuation (usually), lineout from hotplate feeding yamaha spx90 for doubling pitchshift effect, hot plate speaker out to marshall 1960tv with 60s greenback and marshall branded 80s v30 speakers in x pattern, spx90 to asr 100 watt power amp driving srock 1960tv or 1960ax
Yamaha spx90 fed an asr ss power amp and a marshall 1960 cab of any variety i had handy ny given year on the bassist's side of the stage... Big sound