Campbell American Guitars is a boutique electric guitar builder based in Massachusetts, with production originally set up in Pawtucket, Rhode Island. The company was founded by Dean Campbell, starting in 2002 as Greene and Campbell before being renamed Campbell American Guitars in 2005. When Rhode Island's Guild factory in Westerly closed, Campbell hired several of its former craftsmen, which shaped the company's hand-built, small-batch approach.

The lineup centers on a handful of distinctive original designs rather than copies of vintage templates. Core models include the Transitone, a semi-hollow offset with variants like the Nelsonic Transitone and Spaceship Transitone developed with Bill Nelson; the Precix, a solid-body; the chambered Space Biscuit; and the Caledonian. The company has also built signature instruments including the FuZix for David "Fuze" Fiuczynski, the FMan for Charlie Farren, and the EM-5 five-string bass for Evan Marien.

Players associated with the brand include session guitarist Danny Kortchmar, Tanya Donelly of Throwing Muses and Belly, blues guitarist Luther "Guitar Junior" Johnson, and Bill Nelson of Be-Bop Deluxe. Instruments have typically been sold in limited numbers through a small network of dealers and by direct pre-order, giving the brand a reputation as a low-volume builder of player-oriented custom electrics.

Campbell American has 3 products cataloged on Equipboard, including Solid Body Electric Guitars. Their gear is featured by 2 artists, with the strongest followings in Rock, Folk, World, & Country, and Electronic. Notable users include Ray LaMontagne and Bill Nelson.