Jeff Senn Guitars is a Nashville, Tennessee-based luthier operation run by builder Jeff Senn, who managed Gibson USA's repair department before launching his own brand. Senn has spent decades in guitar repair, restoration, and construction, learning the craft from his father — a machinist and woodworker — and later from bass and guitar builder Joe Zon. The company has been building instruments since 2003, with Senn running the shop alongside his wife, Chris Markferding.

The Original Senn line focuses on one-off custom electric guitars that reinterpret classic vintage designs, particularly Fender-inspired shapes, alongside new and unique builds. Signature products include the Model One guitar, the DRB2 Danelectro/Silvertone replacement bridge, and the Model One pickup line developed in collaboration with Lollar Guitars. A more affordable production line, Senn by Eastwood, pairs Senn's designs with Eastwood Guitars for manufacturing and distribution.

Senn instruments have a strong following among Nashville session players and touring guitarists, and have been played by artists including Bruce Springsteen, John Fogerty, Kenny Chesney, Joe Perry, Steve Wariner, Peter Stroud, and Audley Freed.

Jeff Senn has 2 products cataloged on Equipboard, including Solid Body Electric Guitars. Their gear is featured by 3 artists, with the strongest followings in Rock, Folk, World, & Country, and Pop. Notable users include Sarah Jarosz, R.J. Ronquillo, and Jedd Hughes.