SMT Guitars, short for Scientifico Musico Technographique, is a boutique electric guitar builder that produces a limited run of around thirty instruments per year, sold directly rather than through retail stores. The company's designs draw on the work of Paul Bigsby and Nat Daniels (Danelectro), with a touch of Zemaitis in the ornamentation.

The instruments are known for unusual body shapes, pearl inlay work, and build quality aimed at serious players, with visual cues borrowed from fine art, 1940s industrial design, and American hot rod culture. Models documented in guitar reference sources include the SMT Xtreme.

SMT guitars have been built for a number of well-known players, including Andy Gill of Gang of Four, Chris Isaak, and Billy F. Gibbons of ZZ Top.