Alessandro is a high-end guitar amplifier company founded by George Alessandro, based in the Philadelphia, Pennsylvania area. The company began as Hound Dog Amps in 1994 and was renamed Alessandro in 1998, reflecting a shift toward hi-fi–influenced design. Alessandro amps are built around vacuum-tube circuits paired with proprietary components, hi-fi–grade transformers, and high-purity conductors, with hand-made cabinetry offered in woods such as oak, flame maple, cherry, mahogany, walnut, and cocobolo.

The lineup is known for its dog-themed model names — the Beagle, Basset Hound, English Coonhound, Plott Hound, Black 'n Tan, and Blue Tick — alongside models like the Italian and the Dane, plus the more affordable hand-wired Working Dog series. The company also offers speaker cabinets, instrument and studio cables, headphones, and hand-wired restoration and vintage-continuation work. George Alessandro has collaborated with Eminence on signature guitar speakers, including the Eric Johnson Signature EJ1250 alnico speaker.

The brand has a reputation among boutique-amp enthusiasts for meticulous construction and a harmonically rich, dynamic voice. Players associated with George Alessandro's work include Derek Trucks, David Gilmour, and John Mayer.

Alessandro has 4 products cataloged on Equipboard, including Guitar Amplifier Heads, Guitar Potentiometers, and Guitar Amplifier Cabinets. Their gear is featured by 4 artists, with the strongest followings in Rock, Folk, World, & Country, and Blues. Notable users include John Mayer, David Gilmour, and Adam Jones.