Cavagnolo is a French accordion manufacturer founded in 1904 by Domenico Cavagnolo in Vercelli, Italy, before relocating to the Lyon region of France in 1923. The company became one of the leading names in French accordion making, particularly associated with the musette tradition, and its instruments have been played by celebrated accordionists including Gus Viseur, Marcel Azzola, Joss Baselli, and Yvette Horner.

The firm produces both acoustic and digital instruments at its workshop near Lyon. Its acoustic catalog includes chromatic button accordions and piano accordions across lines such as the Compact Super and Professionnel 8, while more contemporary efforts have focused on lightweight builds incorporating carbon-fiber construction. On the digital side, Cavagnolo developed the Digit AiR series and the AiR Symphony arranger module, which use proprietary sound generation aimed at reproducing the response of an acoustic accordion.

The brand is known for its emphasis on bellows compression, ergonomics, and reed treatment, and its instruments are common in French variété, bal-musette, jazz manouche, and chanson contexts. Cavagnolo accordions are distributed through specialist retailers in Europe and beyond.

Cavagnolo has 2 products cataloged on Equipboard, including Synthesizers. Their gear is featured by 2 artists, with the strongest followings in Electronic, Rock, and Pop. Notable users include Martin L. Gore and Jean Michel Jarre.