Clair Brothers is a professional loudspeaker and sound reinforcement brand based in Lititz, Pennsylvania. The company traces its roots to 1966, when brothers Roy and Gene Clair took their public address system on tour with Frankie Valli and the Four Seasons — a job widely credited as the first example of a dedicated sound company touring with a band. Clair Bros. Audio Enterprises, Inc. was formally incorporated in 1970.

The brand is closely associated with large-format touring PA, and is known for introducing the S4 in 1974, an all-in-one four-way single-box loudspeaker with an integrated hanging grid that became a fixture on arena tours for decades. The S4 was refined through the S4 Series II (1982), the long-throw S4P (1983), and later revisions, and has been used on tours for artists including Rod Stewart and the Rolling Stones. Subsequent product lines include the i-Series line-array family (such as the i-5, i-3, and i-DL) and the kiT Series of compact line-array and point-source boxes aimed at installation and smaller touring applications.

Clair Brothers also pioneered innovations that became standards in live production, including early stage monitor designs and hanging arena sound systems. The loudspeaker brand sits alongside Clair Global, the related live-production and touring rental company, and has long been associated with stadium-scale concert sound rather than consumer or studio audio.

Clair Brothers has 4 products cataloged on Equipboard, including Monitors & Accessories, Speakers & Accessories, and Subwoofers & Accessories. Their gear is featured by 3 artists, with the strongest followings in Rock, Pop, and Folk, World, & Country. Notable users include Sting, Elton John, and P!nk.