Manhattan Research, Inc. is the pioneering electronic music company founded by composer and inventor Raymond Scott in 1946. Based in New York, the firm was billed as "Designers and Manufacturers of Electronic Music and Musique Concrète Devices and Systems." Through Manhattan Research, Scott designed and built a remarkable array of custom electronic instruments, including the Clavivox keyboard synthesizer, the Electronium (a self-composing sequencer), the Circle Machine, the Karloff sound-effects generator, Bandito the Bongo Artist, the Bass Line Generator, and the Rhythm Modulator. The Clavivox, completed in the early 1950s, was effectively a keyboard-controlled theremin featuring a vacuum tube oscillator and a three-octave keyboard, with a sub-assembly circuit contributed by a young Robert Moog.

Scott's work at Manhattan Research placed him at the vanguard of electronic music technology. He was among the first composers to use electronic sounds in commercial jingles, producing work for clients including Ford Motor Company, IBM, Sprite, and Hostess. He also composed electronic soundtracks for experimental films by Jim Henson in the mid-1960s. Moog regarded Scott as an important influence on his own synthesizer development, and in 1971, Motown founder Berry Gordy hired Scott as director of electronic music and research, a position he held through 1977.

Manhattan Research's legacy rests on Scott's visionary approach to electronic instrument design and composition at a time when the field barely existed. A posthumous compilation album, Manhattan Research, Inc., released in 2000 on the Basta label, brought renewed attention to Scott's extensive body of unreleased recordings from the 1950s and 1960s. The company's archives are housed at the University of Missouri Kansas City.

Manhattan Research has 3 products cataloged on Equipboard, including Synthesizers and Modular Synthesizers. Their gear is featured by 2 artists, with the strongest followings in Rock, Electronic, and Pop. Notable users include Raymond Scott and Mark Mothersbaugh.