Melbourne Instruments is an Australian synthesizer company based in Melbourne, founded in 2018 by Ian Overliese, Connor Hansen, and David Klopsteins. The company is known for pioneering motorized control surfaces, replacing traditional potentiometers with brushless motors paired with high-resolution optical sensors so that physical knobs can move on their own to reflect preset recalls, automation, and modulation in real time.

The brand's flagship product is NINA, a 12-voice analog multitimbral polysynth with a fully motorized front panel, introduced in 2022. It was followed by DELIA, a bi-timbral motorized hybrid polysynth that combines analog filters with a Macro Oscillator engine offering a wide range of waveform models. Melbourne Instruments also produces the Roto-Control, a standalone motorized MIDI controller designed for use with DAWs, plugins, and external hardware.

The company occupies a niche at the intersection of boutique analog synthesis and high-end interface engineering, and its instruments are sold internationally through retailers such as Vintage King, Perfect Circuit, and Kraft Music. Artists associated with the brand include Jean-Michel Jarre, Matt Johnson of Jamiroquai, and Dâm-Funk.

Melbourne Instruments has 2 products cataloged on Equipboard, including Synthesizers. Their gear is featured by 2 artists, with the strongest followings in Pop, Electronic, and Hip Hop. Notable users include Dam-Funk and Gill Princen.