Sioux Guitars is a small amplifier and effects company based in Sioux City, Iowa. Despite its name, the brand does not build guitars — its catalog centers on handcrafted tube amplifiers, effects pedals, and reverb tanks, along with peripheral merchandise such as apparel and a small in-house record label (Sioux Records).

The company's identity is closely tied to Jensen loudspeakers, and its amp designs lean on Jensen drivers (the C15K 15" Classic Ceramic is cited as a house favorite) paired with unconventional preamp and power-tube combinations. Amps are pitched as versatile enough for electric guitar, bass, electric piano, organ, and harmonica microphones, with an emphasis on affordable, Midwest-built gear rather than boutique pricing.

Sioux Guitars has 22 products cataloged on Equipboard, including Combo Guitar Amplifiers, Multi Effects Pedals, and Solid Body Electric Guitars. Their gear is featured by 9 artists, with the strongest followings in Rock. Notable users include Josh Berwanger, Chuck Dukowski, and Sylvain Sylvain.