Chamberlin is an American electro-mechanical instrument manufacturer founded by inventor Harry Chamberlin, who developed and patented the first tape-replay keyboard between 1949 and 1956. Operating out of Upland and later Ontario, California, the company built keyboards in which every key triggered an individual strip of pre-recorded magnetic tape, pioneering an early form of sampling. Recordings for the tape banks were performed by members of the Lawrence Welk Orchestra.

The catalog is best known for the Musicmaster 600 and Model 300 keyboards, the table-top M1 introduced in 1970, and the Rhythmate — a tape-loop drum machine often credited as the first commercially produced drum machine. The M1 offered higher-quality playback heads and a smaller footprint than competing tape-replay instruments, while the Rhythmate delivered 14 selectable patterns recorded from real acoustic jazz kits, with tempo adjusted by shifting a spindle that altered tape speed.

Chamberlin's tape-replay design directly influenced the British Mellotron, which was reverse-engineered from Musicmaster 600 units brought to England by Chamberlin's salesman Bill Fransen and later resolved through a legal settlement with Bradmatic Ltd. M1 production ended in 1981, with final units assembled in the Chamberlin family garage. Original instruments remain prized by collectors for their warm, character-rich tape tones, and the brand's sound lives on through software emulations such as GForce Software's ChamberTron.

Chamberlin has 5 products cataloged on Equipboard, including Synthesizers and Drum Machines. Their gear is featured by 9 artists, with the strongest followings in Rock, Pop, and Electronic. Notable users include Damon Fox, David Bowie, and Phil Elvrum.