Mezzabarba Custom Amplification is an Italian boutique amplifier maker based in Farnese, on the border of Lazio and Tuscany. The company evolved from Masotti Guitar Devices, founded in 1998, and is led by Pierangelo Mezzabarba, an electrical engineer with a focus on traditional tube-amp design. All products are hand-built in Italy using point-to-point and hand-wired construction.

The brand's catalog centers on high-wattage tube guitar heads such as the M Zero, M Zero Overdrive, Trinity MKII, Skill, Sintesi, and the high-gain Apocalypse, paired with matching 4x12, 2x12, and 1x12 cabinets including the M Zero '69, Cruiser, and Streetfighter. Mezzabarba also produces a small line of guitar pedals under the Nirvana, Even Drive, and Sentinel names, along with an Eric Steckel signature M Zero Overdrive.

Mezzabarba amps have developed a following among professional rock and metal players seeking a modern European take on tube tone, and the company publishes endorsements from a range of touring guitarists across hard rock, progressive, and metal styles.

Mezzabarba has 13 products cataloged on Equipboard, including Guitar Amplifier Heads, Combo Guitar Amplifiers, and Guitar Preamps. Their gear is featured by 7 artists, with the strongest followings in Rock, Metal, and Electronic. Notable users include John Norum, Alessandro Cortini, and Marco Sfogli.