Anywhere 3S allows horizontal scrolling by holding a side button while scrolling, despite lacking a side scroll wheel.

The 2S model features side scrolling, which some users find more efficient for tasks like copy/paste compared to the 3S's side button + wheel method.

The 2S uses the wheel button for scrolling mechanism switching, frustrating users who prefer customizable central button functions like middle-click for opening links.

The "3 for Business" model includes encryption, which may be relevant for programmable button security in business environments.

The 3S version features an 8K DPI sensor and quieter clicks, distinguishing it from the "3 for Business" version.

The rubberized texture on the Master 3S stains easily and wears poorly, especially in lighter color options.

The "3 for Business" model has a brighter click sound compared to the 3S, though neither is particularly loud.

Owners with smaller hands favor Anywhere 3S for comfort, whereas those with larger hands may find it too small.

Without the Options+ software, users are limited to default functions, missing out on custom desktop/screen switching configurations.

The MX2S with "unifying" technology is incompatible with Logitech's "bolt" technology in newer peripherals like MX Keys.

Both the 3 for Business and 3S can connect via Bluetooth or the Bolt receiver, offering flexible connectivity options.

Anywhere 3S is reportedly more responsive than Master 3S on large, high-resolution monitors due to a potentially higher polling rate.

Anywhere 3S is noted to be only $20 more than Anywhere 3, despite providing quieter clicks and magnetic scrolling benefits.

Some owners prefer the 2S over the 3S despite the latter's USB-C charging, as they value the 2S's side scrolling and find the 3S not worth the upgrade.

The "3 for Business" model comes in plain brown cardboard packaging, as opposed to the more decorated box of the 3S, and is primarily sold to business customers.