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Average Price: $3,081

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$1001+

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Based on price data from 2 merchants for "PreSonus StudioLive 64S 64-Channel Digital Mixer and USB Audio Interface". Prices shown reflect NEW condition. Tracking began Apr 2, 2026.

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Description

The PreSonus StudioLive 64S is a game-changer in the realm of digital mixing, offering a staggering 64 channels of pristine audio to elevate both studio and live sound experiences. At the heart of this powerhouse is the quad-core FLEX DSP engine, capable of running 526 simultaneous processors, ensuring your mix is as polished as your vision. With 33 touch-sensitive motorized faders, you can sculpt your sound with precision, whether you’re in the studio laying down tracks or managing a live performance.

Harness the flexibility of 32 Flex Mixes, configurable as aux mixes, subgroups, or matrix mixes, tailored to suit your specific needs. The StudioLive 64S is equipped with 24 DCA groups, providing you with effortless control over complex productions. It’s not just about quantity; the quality shines through with 32 Class A XMAX preamps that deliver studio-grade sound with high headroom and low noise.

For those who need versatile recording options, this mixer has you covered. Record and playback up to 64 channels via USB, and take advantage of the built-in SD card for multitrack recording and virtual soundchecks. Connectivity is seamless with AVB over Ethernet, interfacing smoothly with PreSonus NSB stage boxes and EarMix 16M personal monitor mixers.

The StudioLive 64S also boasts the FLEX FX multi-effects processor, offering eight slots of reverb emulations and delays across eight dedicated effects buses. With advanced scene management and DAW control integration, this mixer is a true partner for any project, big or small.

Key Features:

  • 64-channel digital mixing console with USB 2.0 interface
  • Quad-core FLEX DSP engine with 526 simultaneous processors
  • 32 Flex Mixes configurable as aux, subgroup, or matrix mixes
  • 33 touch-sensitive motorized faders
  • 32 Class A XMAX preamps with high headroom and low noise
  • Built-in SD card recorder for multitrack recording
  • Supports AVB over Ethernet for seamless connectivity
  • FLEX FX multi-effects processor with eight slots for reverb and delays
  • Fat Channel processing with vintage EQ and compressor models
  • 24 DCA groups for managing complex productions
  • Compatible with Studio One, Logic, and Pro Tools through DAW control integration

Product specs

Type Digital Mixer
Channels 64
Inputs - Mic Preamps 32 x XLR-1/4" combo (mic/line)
Phantom Power 32 Channels
Inputs - Line 1 x Dual RCA Stereo (tape), 4 x 1/4" (2 x stereo aux in)
Outputs - Main 2 x XLR (main out), 1 x XLR (mono/center), 2 x 1/4" (monitor)
Outputs - Other 16 x XLR (mix out), 1 x Dual RCA Stereo (tape)
Outputs - Digital 1 x XLR (AES/EBU)
Busses/Groups 32 x FlexMix Buses (aux, subgroup, matrix), 43 total mix buses, 24 x DCA groups
Talkback 1 x XLR (phantom power)
Data I/O 1 x Locking Ethernet (AVB audio network), 1 x RJ45 (network control)
Headphones 1 x 1/4"
USB 1 x Type B (64 x 64)
Computer Connectivity USB 2.0
Bluetooth v4.1
Faders 33 x Touch-sensitive motorized faders
A/D Resolution 24-bit/48kHz
Effects FLEX FX Multi-effects processor, 8 x effects slots, 8 x effects buses
Signal Processing Fat Channel plug-ins, 10 x EQs, 10 x Compressors
Features Metro remote-control (UC 4.2)
Transport Controls Yes
DAW Control Advanced Studio One, MCU Logic emulation, HUI Pro Tools emulation
Screen 7" Touchscreen
Storage SD card recorder (34 track)
Software Studio One Pro, Presonus Capture, UC Surface
Power Source Standard IEC AC cable
Height 6.51"
Depth 22.97"
Width 32.37"
Weight 37.2 lbs.

FAQs

What are the main connectivity options for the PreSonus StudioLive 64S mixer?

The PreSonus StudioLive 64S offers extensive connectivity, including 32 XLR-1/4" combo mic/line inputs, 16 XLR mix outputs, USB 2.0 for 64x64 audio interface, an Ethernet port for AVB audio networking, and digital AES/EBU output.

Is the PreSonus StudioLive 64S mixer compatible with DAWs like Pro Tools and Logic?

Yes, the PreSonus StudioLive 64S features DAW control with HUI emulation for Pro Tools and MCU emulation for Logic, ensuring seamless integration with these popular software platforms.

Can the PreSonus StudioLive 64S be used for live sound applications?

Absolutely, the StudioLive 64S is designed for both live sound and studio recording, offering a powerful digital console with features like AVB networking, motorized faders, and a robust DSP engine suitable for live performances.

Does the PreSonus StudioLive 64S have built-in effects processing?

Yes, it includes the FLEX FX multi-effects processor with eight effects slots and buses, allowing you to load reverb, delay, and other effects for versatile sound shaping.

How does the PreSonus StudioLive 64S handle scene management?

The StudioLive 64S offers advanced scene management with the ability to organize scenes into projects, lock scenes, and use channel safe to protect specific settings, providing streamlined control during live or studio sessions.

What type of preamps are included in the PreSonus StudioLive 64S?

The mixer features 32 recallable XMAX preamps known for their high headroom and transparent sound quality, making them ideal for capturing detailed audio in various recording environments.

Sweetwater

Sweetwater

PreSonus StudioLive 64S Digital Mixer Overview

Video thumbnail for PreSonus StudioLive 64S Digital Mixer Overview by Sweetwater

PreSonus StudioLive 64S Digital Mixer Overview

Sweetwater

Sweetwater

Video thumbnail for PreSonus StudioLive 64S First Look With PreSonus Specialist - Extended Video by Production Expert

PreSonus StudioLive 64S First Look With PreSonus Specialist - Extended Video

Production Expert

Production Expert

Video thumbnail for PreSonus—Introducing the StudioLive 64S by PreSonus Audio Electronics

PreSonus—Introducing the StudioLive 64S

PreSonus Audio Electronics

PreSonus Audio Electronics

Video thumbnail for InfoComm 2019: PreSonus Presents StudioLive 64S 64-Channel Digital Mixer and USB Audio Interface by rAVe [PUBS]

InfoComm 2019: PreSonus Presents StudioLive 64S 64-Channel Digital Mixer and USB Audio Interface

rAVe [PUBS]

rAVe [PUBS]

Video thumbnail for PreSonus 64-channel StudioLive Series III S by fohtv

PreSonus 64-channel StudioLive Series III S

fohtv

fohtv

Reviews

PROS

  • Seamless integration with Studio One and other PreSonus ecosystem products

  • Exceptional sound quality and routing flexibility

  • AVB networking simplifies setup with CAT5 cabling

  • Personal monitoring options enhance user control

  • Perfectly suited for both studio and live band settings

  • Easy for volunteers to manage in large setups like churches

  • Versatile and expandable, tailored to different workflows

  • Sturdy build ensures long-term durability

  • Eliminates need for bulky outboard gear with onboard features

  • Improves livestream audio quality significantly

CONS

  • Onboard capture card feature may not meet all standards

  • Initial learning curve for users transitioning from other systems

Owner Insights

We analyzed real musician discussions from forums and Reddit to find what players love, question, and tweak about PreSonus StudioLive 64S 64-Channel Digital Mixer and USB Audio Interface.

Use cases and applications

  • The mixer supports saving to an SD card for practice sessions, allowing virtual soundchecks when away from the studio.

    Source
  • StudioLive's integration with Studio One is highly praised, though initial setup may require YouTube tutorials for optimal configuration.

    Source
  • The mixer is favored for home studios due to its robust software integration and comprehensive feature set, despite its complexity for live events.

    Source

User experience

  • Some users have experienced crashes and slow response, making it less ideal for demanding live performances.

    Source
  • Owners appreciate the ability to add a stage box to expand input capabilities without investing in a larger desk immediately.

    Source
  • Owners appreciate the mixer’s processing power and sound quality, though some find the interface less intuitive compared to Behringer or Yamaha systems.

    Source

Features and functionality

  • Preamps are described as clean but thin, similar to Behringer's, lacking the fullness found in Apollo or Audient models.

    Source
  • The mixer integrates effortlessly with DAWs like Ableton, providing simultaneous multitrack recording without latency.

    Source
  • The StudioLive 64S offers Virtual Soundcheck using PreSonus Capture software, allowing users to record and playback all channels for practice and refinement.

    Source
  • Real-time EQ, gates, and compressors eliminate the need for a computer during band practice, offering immediate sound control.

    Source
  • Flying faders and multiple aux mixes allow individual in-ear monitor mixes, with faders snapping to their respective mixes for easy volume adjustments.

    Source
  • The FatChannel offers emulations of popular compressors like the LA-2A and 1176, providing users with versatile sound-shaping options.

    Source

Comparisons

  • Behringer X32 is recommended for live environments due to superior reliability and faster response times compared to StudioLive.

    Source
  • The PreSonus StudioLive is likened to the RME Fireface UCX II, with both offering similar functionality but differing in physical controls and I/O capacity.

    Source
  • Compared to the A&H Qu series and Behringer/Midas X32/M32, the StudioLive Series III is seen as a midrange product offering good value, though some prefer alternatives for professional use.

    Source
  • The StudioLive 64S is compared to earlier PreSonus models, with improvements in reliability, though still not meeting Midas or Yamaha standards in professional settings.

    Source

Build quality

  • Some users report LED issues and routing problems, with concerns about build quality and reliability, especially in live settings.

    Source

Setup and maintenance

  • Firmware updates are crucial, as they address early bugs and improve functionality, but they can also introduce new issues, requiring cautious updating.

    Source
  • Regular cleaning with compressed air is recommended to prevent overheating, as the mixer lacks internal fans and can be sensitive to dust buildup.

    Source

Software and compatibility

  • The mixer integrates with DAWs via USB and supports Mackie Control and HUI protocols, enabling control of mixer functions from software interfaces.

    Source

Critic Reviews

Review: PreSonus StudioLive 64S Digital Mixer - Church Production Magazine

churchproduction.com

PreSonus StudioLive 64S is a powerhouse mixer that significantly ups the ante from its predecessor with 64 channels and impressive processing capabilities, all packed into the same compact frame. The quad-core Flex DSP Engine and AVB networking make it a versatile choice for live sound and studio production, particularly appealing to budget-conscious users like churches. The touch-sensitive motorized faders, intuitive touchscreen, and robust effects engine enhance the user experience, although some might find AVB management and bus routing require a learning curve. While it lacks multi-band processing, the overall value and feature set make it a standout in its class. PreSonus continues to blur the lines between hardware and software, offering a seamless ecosystem that integrates well with their software products like Studio One. Despite a couple of minor caveats, this mixer is a testament to PreSonus' commitment to delivering high-quality gear at accessible prices.

positive

Road Test: The New PreSonus StudioLive 64S - Page 2 of 2 - ProSoundWeb

prosoundweb.com

The PreSonus StudioLive 64S packs a punch with its impressive channel count and integration with StudioOne DAW, making it a strong contender for both live and studio settings. Its compact design and intuitive setup are standout features. However, the interface's growing pains are evident, especially with an overly sensitive firmware rollback feature and high latency issues in AVB implementation, which might concern professionals relying on in-ear monitors. The console’s backlit controls are helpful, though flickering LEDs could be distracting. Future firmware updates promise to address these software-related gaps, suggesting potential for enhanced functionality.

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