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Average Price: $80

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$150+

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Based on price data from 1 merchant for "Two Notes Audio Engineering GENOME". Prices shown reflect NEW condition. Tracking began Apr 2, 2026.

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Description

Dive into a world of sonic possibilities with the Two Notes Audio Engineering GENOME, a comprehensive amp simulator plugin designed to elevate your in-the-box or hybrid setups. Whether you're a seasoned guitarist or a budding bassist, GENOME offers a dynamic ecosystem that encapsulates everything from virtual amps and pedals to studio-grade effects, empowering you to craft your signature sound with ease.

At the heart of GENOME lies the innovative CODEX Unification Engine, seamlessly integrating AI-generated amp and pedal models. Compatible with Neural Amp Modeller (NAM), AIDA-X, and Proteus captures, this engine ensures a futuristic approach to tone shaping. Coupled with the Tube-Stage Modeling (TSM™) Engine, players can explore a realm of pristine preamp models and customizable tube poweramp setups. From the subtle warmth of a 6L6 tube to the roaring gain of a KT88, GENOME's versatility knows no bounds.

For pedal enthusiasts, GENOME offers an extensive library of meticulously crafted overdrive, distortion, delay, and modulation effects. Whether you seek the vintage charm of a classic phaser or the edgy punch of a modern overdrive, the PEDAL Engine delivers with precision.

The DynIR™ Engine further redefines virtual cabinet technology, bringing you closer to authentic studio-grade tones. With 600+ virtual cabinets and a plethora of microphone options, achieving the perfect mic placement has never been simpler.

Key Features:

  • CODEX Unification Engine with AI model compatibility
  • Tube-Stage Modeling (TSM™) Engine with customizable tube poweramp models
  • Comprehensive PEDAL Engine with overdrive, distortion, delay, and modulation effects
  • DynIR™ Engine with 600+ virtual cabinets and studio-grade microphones
  • Intuitive, guitar-centric interface for seamless tone crafting
  • Extensive STUDIO FX suite including compressor, EQ, delay, and reverb
  • Dual-Lane processing for effortless parallel processing
  • Includes 5 DynIR™ Captures, 40 Microphones, 13 PEDALS, 12 TSM™ Amplifiers, and 50+ AI Amp Captures
TwoNotesTV

TwoNotesTV

Introducing GENOME

Video thumbnail for Introducing GENOME by TwoNotesTV

Introducing GENOME

TwoNotesTV

TwoNotesTV

Video thumbnail for Two Notes GENOME: The Future of Guitar Amp Software ?? by The Studio Rats

Two Notes GENOME: The Future of Guitar Amp Software ??

The Studio Rats

The Studio Rats

Video thumbnail for Checking Out Two Notes GENOME! by Riffs, Beards & Gear

Checking Out Two Notes GENOME!

Riffs, Beards & Gear

Riffs, Beards & Gear

Video thumbnail for Two Notes Audio - Genome : Metal Demonstration by Loody Bensh

Two Notes Audio - Genome : Metal Demonstration

Loody Bensh

Loody Bensh

Video thumbnail for Meet The Two Notes Engineering Genome | JayLeonardJ by JayLeonardJ

Meet The Two Notes Engineering Genome | JayLeonardJ

JayLeonardJ

JayLeonardJ

Video thumbnail for More Than Just A Guitar Rig! | Two Notes Genome! by High Impakt Audio

More Than Just A Guitar Rig! | Two Notes Genome!

High Impakt Audio

High Impakt Audio

Video thumbnail for Genome by Two Notes Audio Engineering (No Talking) by Elektronick Musick

Genome by Two Notes Audio Engineering (No Talking)

Elektronick Musick

Elektronick Musick

Reviews

Owner Insights

We analyzed real musician discussions from forums and Reddit to find what players love, question, and tweak about Two Notes Audio Engineering GENOME.

Features and functionality

  • The Two Notes GENOME offers users 26 virtual cabinets, enhancing versatility for those who register their Captor 8.

    Source
  • The codex section provides limitless amp profiles, offering flexibility in shaping tones, including a "dem bones" preset with JCM800 and a unique Recto.

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Software and compatibility

  • Owners of the Captor 8 can download GENOME software by registering the unit's serial number, found on the base of the device.

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  • Future updates are expected to include licensed amp models with full controls, enhancing GENOME's appeal for those seeking real-world amp counterparts.

    Source

Setup and maintenance

  • Users experiencing phasey or hollow sounds should check if the cab sim is disabled on the Captor when using an IR in a DAW.

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Use cases and applications

  • GENOME is recommended for DI use with guitar preamps, offering a more versatile sound than smaller amps like the Laney 10 Cub.

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  • GENOME is suitable for quick takes or overdubs, but some users prefer Cabinetron for loading IRs due to its familiarity and ease of use.

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  • GENOME's cab IRs are favored for mixing, though users prefer actual amps or other plugins for zero-latency recording through interfaces like UA Apollo.

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User experience

  • Users note potential phase issues when recording multiple tracks or using multiple IRs; flipping the phase or using a single IR can resolve this.

    Source
  • Owners using Fractal FM3 or Kemper find GENOME's amp sims lacking compared to their preferred digital rigs for live performances.

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Comparisons

  • Users find the GENOME's interface improvements over Wall of Sound beneficial, though they prefer other amp sims like Brainworx for high-gain tones.

    Source

Critic Reviews

Two Notes Genome review – a no-nonsense guitar plugin

guitar.com

Two Notes Audio Engineering's GENOME is a compelling VST plugin that balances affordability with quality. Its streamlined interface and intuitive controls make it user-friendly, while the sound quality, particularly for clean tones, impresses with its attention to detail. However, the effects library is limited compared to competitors, and the cost of expansions can quickly add up. Notably, the absence of pitch-shifting effects is a drawback that may frustrate some users. Still, the compatibility with third-party captures enhances its value, making GENOME an attractive option for musicians seeking a focused signal chain without breaking the bank.

positive

Two Notes Genome review | GuitarPlayer

guitarplayer.com

Two Notes Audio Engineering's GENOME delivers an impressive modeling experience, combining extensive amp and pedal simulations within an intuitive interface. The dual-generation amp tone and the ability to recreate the sound of any amp elevate it as a top-tier plugin for DAWs. However, users should be aware that compatibility isn't universal—check system requirements before diving in. For its price point, GENOME stands out as a versatile and creative tool, making it a worthy addition to any guitarist's arsenal despite its minor limitations.

positive

Two notes Genome

soundonsound.com

Two Notes Audio Engineering's Genome is a powerhouse of tonal possibilities, combining traditional amp modeling with innovative AI-driven captures for a versatile sound palette. The interface is intuitive, offering deep editing capabilities across a range of effects and models. While the quality of sound is commendable, the lack of a dedicated noise gate option can be a drawback for some users. Additionally, the inconsistent terminology in the manual may lead to confusion. Nonetheless, Genome’s ability to integrate various modeling technologies in one plugin sets it apart, making it a worthy investment for guitarists looking to enhance their sonic arsenal.

positive

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Artist usage

Add artist
See how R.J. Ronquillo uses Two Notes Audio Engineering GENOME

R.J. Ronquillo

Guitarist, Podcasters & Streamers

Stone Sour

...
Verified via YouTube

In a YouTube video titled "Two Notes GENOME Guitar Software," R.J. Ronquillo demonstrates his use of the Two Notes Audio Engineering GENOME, providing direct insight into the functionality and features of this amp simulator plugin.

Genre Usage

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