In this video at 4:19 we can see Akai S2000 Sampler

Isham's 'orchestra pit' is, however, no slouch, with several Akais (S3200, CD3000, S1000, S1000PB and three S2000s), three Emu E4Xs, three Roland S760s, plus a selection of older units. "They each have their own characteristics — the Akais have a tremendous transient response, and for percussion they're just brilliant; the Rolands have a warmth about them. I also have so many because of the various different programmers that work in the different formats. Eric Persing of Spectrasonics pretty much works for Roland, and he's just so good that I had to have some Roland gear to take advantage of his wonderful work."

At 5:48 an Akai S2000 can be seen under his Akai S950.

In this video Phineus II provides a tutorial for the Akai S2000.

In the Bandcamp description of Role Model, Cex lists the gear he used which includes an Akai S2000 sampler.

Resident Advisor, May 28, 2019:

I was made redundant from a job I had at a DIY store around that time. I was getting something like £400 a month and they gave me three months pay as severance. I spent it all on an S2000. My parents were like, "What have you done!" And I'm like, "Yeah, I got this massive cream box that I don't know how to use." But I was so happy to have a real sampler because I was botching it for years.

The MIRAGE had to be phased out almost immediately when we started touring. Too heavy, too awkward to load floppy disks on stage, too weird to trust, too outdated to repair quickly. So the Akai S2000 entered the picture, a rack-mountable sampler to put our long loops and keyboard sounds on (we trigger it with a MIDI keyboard controller). So I re-sampled all the sounds from the MIRAGE on to the new sampler which sucked and for some reason it was hard to get them all trimmed right. The Akai S2000 compared to the MIRAGE is like a fighter jet vs. a rotary phone. It has so much more memory, more editing features and other crazy shit. Our rudimentary use of it as a sound bank for the keyboard doesn’t even scrape the surface of its immense brain! We basically use it as extra memory for the MPC when we have it maxed out, or to play keyboard parts live. And now we have drum pads to trigger its samples!

The Akai S2000 is Seen at 2:04

Gear

Kurzweil K2500 (two) "I use one K2500 as my controller keyboard and I have an additional rackmount K2500. I use those to control my sound library of real orchestral sounds." Akai S2000 Roland JV1080 "I use this with the orchestra expansion card for some of the orchestral sounds that are mostly in the background — in other words those that don't require so much authenticity. It allows me to layer up sounds without having to use up any of the memory I need for my better CD‑ROM orchestral samples." Studio Electronics ATC1 "This one I use when there's a need for analogue sounds. You can switch from one type of sound to another depending on what cartridge you put in." Roland Juno 106 "I used the Juno 106 for Mercenaries and a bunch of other titles that needed more industrial types of sounds." Tech 21 SansAmp PSA1 "This is great for recording guitar sounds. It has a whole bunch of different guitar distortions and effects and plugs straight into the board — you don't have to go through a separate amplifier, but it creates the sound just as well." Alesis ADAT XT "Occasionally when I have all the samplers filled up and I don't have any more memory I dump them on to different tracks on the ADAT and record them that way." Tascam DA30 DAT recorder JVC Pro Series Digital S video deck "I use this half‑inch deck to sync up films and timecode." Apple Power Mac 4400 running MOTU's Digital Performer "I've been trying various different sequencers to see which one I like the best and, although they all have their pros and cons, I find that Digital Performer works really well for what I'm doing." Digidesign Pro Tools "I don't use Pro Tools that much. Sometimes I will if I need to sync up different dialogue and sound effects to the music, but mostly I do the final mix onto DAT and if necessary I'll load that back into Pro Tools to burn CDs."

In a YouTube video titled "Meng Syndicate - 3 Times Chaos (Cash Kru Remix) [Ableton Live 12 + Akai S2000]," Cash Kru demonstrates the use of the Akai S2000 in the creation of a remix for the track "3 Times Chaos" by Meng Syndicate.