M-Audio Oxygen 49 MKIV MIDI Keyboard Controller

$168.50 Price Tier: Budget

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Page last updated Jul 04, 2026

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We compare 600+ stores and found this item at 1 store. Prices updated July 4, 2026.

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4.0 (5)

$168.50 2 available New

$55.00 3 available Used

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Average Price: $112

Budget/Beginner

$200

$501+

Price Tier

In the MIDI Keyboard Controllers category, M-Audio Oxygen 49 MKIV MIDI Keyboard Controller is priced in the Budget/Beginner range. This is great gear to get started with or for creators on a budget.

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Description

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Designed with both novice musicians and seasoned producers in mind, the M-Audio Oxygen 49 MKIV MIDI Keyboard Controller offers a seamless blend of intuitive design and advanced functionality. This 49-key velocity-sensitive controller is perfect for crafting expressive performances and complex compositions. With its comprehensive range of controls, including eight assignable knobs, nine faders, and transport buttons, the Oxygen 49 MKIV provides unparalleled control over your digital audio workstation (DAW).

The keyboard controller is equipped with a suite of production software, making it an excellent tool for both studio and live performances. Its compatibility with most DAWs ensures that you can easily integrate the Oxygen 49 MKIV into your existing setup. The built-in preset editor also allows you to customize your control assignments, providing a personalized experience tailored to your creative workflow.

The M-Audio Oxygen 49 MKIV shines in its ability to enhance your music production process. Whether you're triggering clips, adjusting levels, or manipulating effects, the Oxygen 49 puts the power of creativity at your fingertips. The controller's compact and lightweight design makes it an ideal choice for musicians on the go, ensuring you never miss a beat during your creative journey.

Key Features:

49 full-size, velocity-sensitive keys for a responsive feel
8 assignable knobs and 9 faders for detailed control
Dedicated transport and track selection buttons
Includes production software for seamless integration
Compatible with popular DAWs, including Ableton Live, Pro Tools, and Logic
USB-powered with plug-and-play connectivity
Built-in preset editor for custom control assignments

Product specs

Brand	M-Audio
Model	Oxygen 49 MKIV MIDI Keyboard Controller
Year	2016 - 2020
Made In	United States
Categories	Keyboard MIDI Controllers, Pad MIDI Controllers
Analog / Digital	Digital
Key Size	Full Size
Keyboard Action	Synth Action
MIDI I/O	USB MIDI
Number of Keys	49 Keys
Number of Pads	8 Pads

FAQs

Is the M-Audio Oxygen 49 MKIV compatible with major DAWs like Ableton Live and FL Studio?: Yes, the M-Audio Oxygen 49 MKIV is compatible with major DAWs including Ableton Live, FL Studio, and others. It includes DirectLink technology for seamless integration and control of your DAW's parameters.
What type of keys does the M-Audio Oxygen 49 MKIV have?: The M-Audio Oxygen 49 MKIV features full-size, synth-action keys, providing a responsive and versatile playing experience suitable for various musical styles.
How does the M-Audio Oxygen 49 MKIV connect to a computer?: The M-Audio Oxygen 49 MKIV connects to a computer via USB MIDI, allowing for easy integration with your digital audio workstation and other music production software.
Does the M-Audio Oxygen 49 MKIV have velocity-sensitive pads?: Yes, the M-Audio Oxygen 49 MKIV is equipped with 8 velocity-sensitive pads, enabling dynamic and expressive beat-making and sample triggering.
Can the M-Audio Oxygen 49 MKIV be powered without a computer?: The M-Audio Oxygen 49 MKIV requires a USB connection for power, typically provided by a computer. However, it can also be powered using a USB wall adapter for standalone use with external MIDI gear.

Videos

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Adventures in Creative Software

How to Program Your M-Audio Oxygen (Mk IV) Midi Controller

Adventures in Creative Software

Feel + Functionality! |M-Audio Oxygen 49 MKIV Midi Controller Review!|

John Mike

Reviews

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PROS

Smooth and precise pitch and mod wheels enhance playability
Offers a substantial upgrade from smaller models like the Oxygen 25
Includes 9 sliders, providing versatile control options
USB and MIDI jacks ensure flexible connectivity
Light and compact design suitable for small studio setups
Excellent tactile feel, appreciated by seasoned players

CONS

Lacks a charger, which can be inconvenient for some users
Confusion with product generation might lead to purchasing the wrong model

Owner Insights

We analyzed real musician discussions from forums and Reddit to find what players love, question, and tweak about M-Audio Oxygen 49 MKIV MIDI Keyboard Controller.

Comparisons

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The Akai MPK Mini and Launchkey Mini are recommended alternatives for better key feel and functionality compared to older Oxygen models.
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Value and pricing

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A used Oxygen 49 MKIV at $50 is considered a fair deal if it's the MK3, but older models should be priced lower.
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Owners frequently highlight the Oxygen 49's affordability, with many stating it's hard to beat the price for the features offered.
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Software and compatibility

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Older Oxygen models may face USB driver issues, impacting compatibility with modern systems.
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A unique issue was reported where the Oxygen 49 stops sending MIDI signals to a specific MacBook Pro, suggesting potential compatibility quirks with certain setups.
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User experience

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Some owners report key contact failures, turning the keyboard into a non-functional unit if replacements aren't available.
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One owner reports long-term durability, stating the keyboard has survived five relocations without issues.
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Some owners mention that the action of the keys lacks resistance, rating the key action as 7/10, indicating it's satisfactory but not exceptional.
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Features and functionality

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The bundled software is often missing from second-hand purchases, which affects the value of older models.
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The Oxygen 49 MKIV lacks MIDI DIN ports, necessitating a USB MIDI host like a computer for use with external devices.
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The keyboard has synth-action keys, which may not suit those seeking a piano-like feel.
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No aftertouch capability is a noted limitation, affecting expressive performance potential.
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Users appreciate the ability to assign any fader, knob, or wheel, enhancing customization and workflow in FL Studio.
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