Pricing and availability
We compare 600+ stores and found this item at 9 stores. Prices updated .
Store
Reviews
Price
Average Price: $250
Standard/Professional
$200
$501+
Price Tier
Budget
Standard
High-end
Price History
Based on price data from 7 merchants for "M-Audio Oxygen Pro 49". Prices shown reflect NEW condition. Tracking began Apr 2, 2026.
* Product prices and availability are updated by Equipboard every 24hrs and are subject to change. Equipboard may receive compensation for purchases made at participating retailers linked on this site. This compensation does not affect what products or prices are displayed, or the order of prices listed. For more information, please refer to our affiliate disclosure.
Description
The M-Audio Oxygen Pro 49 is your go-to MIDI controller for both studio and on-the-go music production. This powerful, 49-key USB-powered MIDI controller is packed with features to streamline your creative process and elevate your music-making experience. With its velocity-sensitive, semi-weighted keys with aftertouch, it offers a responsive and expressive playing experience that rivals higher-end models. The easy-to-read OLED screen and intuitive layout ensure that you can focus on your music rather than getting lost in complex settings.
Designed with the modern music creator in mind, the Oxygen Pro 49 includes 16 RGB backlit, velocity-sensitive pads with Note Repeat, perfect for beat production and clip launching. The 8 assignable knobs and 9 faders provide tactile control over your DAWs and virtual instruments, making it easier than ever to bring your ideas to life. The Smart Chord and Smart Scale modes remove technical barriers, letting you focus on creativity by simplifying chord voicings and eliminating wrong notes.
With its Auto-Mapping feature, this controller seamlessly integrates with all major DAWs like Pro Tools, Ableton Live, and Logic, while the included software suite offers a comprehensive set of tools to kickstart your projects. Whether you're an experienced producer or just starting out, the M-Audio Oxygen Pro 49 ensures you have everything you need for a professional workflow.
Key Features:
- 49 best-in-class, velocity-sensitive, semi-weighted keys with aftertouch and assignable zones
- 16 RGB, backlit, assignable, velocity-sensitive pads with Note Repeat
- 8 assignable knobs for controlling virtual instruments, mix plugins, DAW controls, and more
- 9 assignable faders for controlling levels and perfecting your final mixes
- Smart Chord mode enables playing of enharmonic or custom chord voicings
- Smart Scale mode eliminates wrong notes, making it easy to craft a perfect song
- Arpeggiator with Type, Octave, Gate, and Swing controls
- Ergonomically designed pitch and modulation wheels & 1/4” sustain pedal input
- USB-MIDI connection and 5-pin MIDI Output for controlling external MIDI gear
- Intuitive layout featuring an OLED screen for quick control edits
- Includes MIDI editor software and a complete software production package: Pro Tools | First M-Audio Edition, MPC Beats, and Ableton Live Lite
- Virtual instrument collection from AIR Music Tech, including Hybrid 3, Velvet, Mini Grand, Vacuum, Boom, and DB-33
- A collection of Expansion Packs from Akai Professional's legendary MPC Series
Owner's manual
M-Audio Oxygen Pro 49 User ManualProduct specs
| Available since | November 2020 |
| Aftertouch | Yes |
| Split Zones | 1 |
| Layer function | No |
| Pitch Bend / Modulation | Yes |
| Rotary Encoder | 8 |
| Fader | 9 |
| Pads | 16 |
| Display | Yes |
| Sustain Pedal Connection | Yes |
| USB-port | Yes |
| Mains Operation | No |
| Battery Operation | No |
| Bus-Powered | Yes |
| Dimensions | 800 x 264 x 84 |
| Weight in kg | 4,2 kg |
| Special Features | N/A |
FAQs
-
Does the M-Audio Oxygen Pro 49 work with Ableton Live?
-
Yes, the M-Audio Oxygen Pro 49 is compatible with Ableton Live and comes with Ableton Live Lite software, making it easy to integrate into your DAW setup.
-
What are the key features of the M-Audio Oxygen Pro 49?
-
The M-Audio Oxygen Pro 49 features 49 velocity-sensitive, semi-weighted keys with aftertouch, 16 pads, 8 rotary encoders, and 9 faders, offering extensive control for music production.
-
Is the M-Audio Oxygen Pro 49 suitable for live performances?
-
Yes, the M-Audio Oxygen Pro 49 is well-suited for live performances with its semi-weighted keys, aftertouch, and comprehensive control options, allowing for expressive and dynamic play.
-
Can the M-Audio Oxygen Pro 49 be powered without a computer?
-
The M-Audio Oxygen Pro 49 is bus-powered via USB and cannot be powered independently without a computer or USB power source.
-
Does the M-Audio Oxygen Pro 49 have aftertouch?
-
Yes, the M-Audio Oxygen Pro 49 features aftertouch, allowing for expressive control over your sound by responding to the pressure applied to the keys after they are pressed.
Videos
Eric C. Powell Music
M-Audio Oxygen Pro 49 MIDI Controller - Setup and Demo
Reviews
PROS
-
High-quality build and durable
-
Versatile with many DAW presets included
-
Semi-weighted keys feel realistic and responsive
-
Standalone functionality without a computer
-
Zone aftertouch with 4 MIDI zones and presets
-
Extensive DAW control features, especially with Reaper
-
Adjustable sensitivity on pads
-
Built-in arpeggiator and extensive control options
-
Good value for the price
CONS
-
Software issues with Mac OS Sonoma
-
Complicated setup process for firmware and software
-
Drum pad programming in Logic is cumbersome
-
Tempo synchronization issues with Logic
-
Small screen with limited functions
-
Pitch drift problem over time
-
Aftertouch requires significant pressure to activate
Owner Insights
We analyzed real musician discussions from forums and Reddit to find what players love, question, and tweak about M-Audio Oxygen Pro 49.
Setup and maintenance
User experience
-
Owners appreciate the improved feel of the encoders and sliders compared to previous M-Audio models.
Source -
Users report initial difficulty with programming presets, despite years of MIDI controller use.
Source -
Support response from M-Audio can be slow, with some users waiting extended periods for assistance.
Source -
It's noted that the Oxygen Pro 49 has not been reported to suffer from the encoder problems that plagued the M-Audio Code series.
Source
Software and compatibility
-
ItsGratuiTous offers a free MIDI Script specifically for the Oxygen Pro to enhance FL Studio integration.
Source -
Reaper users achieved success by setting the DAW to "Mackie Universal" control mode, avoiding MIDI3 output to prevent unusual behaviors.
Source -
Automapping issues are reported in FL Studio, requiring users to create custom scripts for functionality.
Source
Features and functionality
-
Preset Mode, not DAW Mode, is recommended for smoother operations in FL Studio.
Source -
The Preset Editor requires enabling advanced options for full functionality, allowing custom preset creation.
Source -
The M-Audio Oxygen Pro 49 features semi-weighted keys and channel aftertouch which are highlighted as improvements over the original Oxygen series.
Source -
The pitch wheel is noted for lagging and not tracking accurately, affecting quick pitch changes.
Source
Build quality
Use cases and applications
-
It's mentioned that the Oxygen Pro 49 provides a good beatmaking experience when used with Virtual Instruments in DAWs like FL Studio.
Source
Critic Reviews
5.0 out of 5
Based on 0 Reviews and 4 Ratings
Artist usage
Add artist
At the 2:00 mark of the video, Cameron Winter is seen using the M-Audio Oxygen Pro 49, identifiable by the distinct arrangement of knobs and sample pads on the left side.
Genre Usage
Based on how artists on Equipboard use this gear, it is most commonly found in the following genres.
Used With
Based on how musicians on Equipboard use M-Audio Oxygen Pro 49, it is most commonly used with the following gear.
More M-Audio MIDI Keyboard Controllers
Accessories & Related Items
Community setups
Similar
Gear Guides
Most Popular MIDI Keyboard Controllers
Most Popular Brands
-
Added to Equipboard on by
kur0Gear IQ 82
-