M-Audio Oxygen 49 MKV MIDI Keyboard Controller

$169.00

4.6 (1009)

$169.00 New

$154.50 Used (Like New)

$141.07 9 available New

$95.52 3 available Used

5.0 (11)

$199.00 $169.00 $30.00 · All time low

$199.00

$199.00 $169.00 $30.00 · All time low

4.7 (15)

$135.00 $134.00 $1.00 · All time low

£122.00

Average Price: $157

Budget/Beginner

$200

$501+

Price Tier

In the MIDI Keyboard Controllers category, M-Audio Oxygen 49 MKV MIDI Keyboard Controller is priced in the Budget/Beginner range. This is great gear to get started with or for creators on a budget.

Budget

Standard

High-end

Price History

Based on price data from 6 merchants for "M-Audio Oxygen 49 MKV MIDI Keyboard Controller". Prices shown reflect NEW condition. Tracking began Apr 2, 2026.

^* Product prices and availability are updated by Equipboard every 24hrs and are subject to change. Equipboard may receive compensation for purchases made at participating retailers linked on this site. This compensation does not affect what products or prices are displayed, or the order of prices listed. For more information, please refer to our affiliate disclosure.

Description

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Introducing the M-Audio Oxygen 49 MKV MIDI Keyboard Controller, a game-changer in the world of music production. This controller isn't just a keyboard; it's a comprehensive tool that puts the power of music creation at your fingertips. The Oxygen 49 MKV is designed for artists who want to improve their workflow and create cutting-edge sounds, whether on stage or in the studio.

The Oxygen 49 MKV controller is packed with powerful features essential for creating and producing music. Experience full control with Note Repeat, a staple in beat production, and full velocity control of keys and pads. The eight assignable knobs and nine assignable faders open a world of precision in music creation, making your signature sound professional and modern.

The built-in Arpeggiator adds excitement and movement to your music quickly and easily, affecting anything you play on the keys from any virtual instrument in your DAW. With the Smart Chord and Smart Scale features, you can play full chords with a single key press and play the exact notes within a chosen scale, unleashing your unlimited creativity.

The Oxygen 49 MKV works smoothly with all major DAWs and includes presets for all the virtual instruments and plugins included. With this keyboard controller, a new world of creative production is at your fingertips.

Key Features:

49 velocity-sensitive keys
8 velocity-sensitive trigger pads with Note Repeat function
8 assignable knobs and 9 assignable faders
Smart Chord & Smart Scale features
Built-in Arpeggiator with control for type, octave, gate, and swing
Auto-mapping for creative DAW control
Works with all major DAWs
Includes Software package: Ableton Live Lite, MPC Beats, 2 virtual instruments from AIR Music Technology (Hybrid, Mini Grand), 5 MPC Beats Expansion Packs, and MIDI Editor software
USB 2.0 (bus-powered)
Sustain pedal input
LC display
Pitch bend and modulation wheels

Owner's manual

M-Audio Oxygen 49 MKV MIDI Keyboard Controller User Manual

Product specs

Type	Keyboard Controller
Number of Keys	49
Type of Keys	Full-size, Synth
Velocity Sensitive	Yes
Pads	8 x Back-lit Pads
Other Controllers	Pitchbend, Mod Wheel
Encoders/Pots	8 x Assignable Knobs
Faders	9 x Assignable Faders
Dedicated Transport Control	Yes
Pedal Inputs	1 x 1/4" (sustain)
MIDI I/O	USB
USB	1 x Type B
Software	Melodics, Skoove, Ableton Live Lite, Akai MPC Beats, Virtual Instruments
Hardware Requirements - Mac	Intel Core 2 Duo or higher, 4GB RAM minimum
Hardware Requirements - PC	64-bit Intel Core 2 Duo / AMD Multi-core or higher, 4GB RAM minimum
OS Requirements - Mac	OS X 10.11.6 or later
OS Requirements - PC	Windows 7 SP1 or later
Power Supply	USB bus powered
Height	3.6"
Width	32.04"
Depth	9.6"
Weight	6.72 lbs.

FAQs

What software is included with the M-Audio Oxygen 49 MKV?: The M-Audio Oxygen 49 MKV comes with a suite of software including Ableton Live Lite, Melodics, Skoove, Akai MPC Beats, and several virtual instruments, providing a comprehensive package for music creation right out of the box.
Is the M-Audio Oxygen 49 MKV compatible with popular DAWs?: Yes, the M-Audio Oxygen 49 MKV is compatible with popular DAWs such as Ableton Live, Logic Pro, and Pro Tools, allowing seamless integration into most digital music production setups.
How many assignable controls does the M-Audio Oxygen 49 MKV have?: The M-Audio Oxygen 49 MKV features 8 assignable knobs, 9 assignable faders, and 8 back-lit pads, offering extensive control over your DAW and virtual instruments.
Can the M-Audio Oxygen 49 MKV be powered without a computer?: The M-Audio Oxygen 49 MKV is USB bus-powered, meaning it requires a USB connection to a computer or a USB power adapter to function.
Are the keys on the M-Audio Oxygen 49 MKV velocity-sensitive?: Yes, the M-Audio Oxygen 49 MKV features full-size, velocity-sensitive synth-action keys, allowing for expressive playing dynamics.
Does the M-Audio Oxygen 49 MKV have a sustain pedal input?: Yes, the M-Audio Oxygen 49 MKV includes a 1/4" input for connecting a sustain pedal, enhancing the expressive capabilities of your performance.

Videos

Add video

M-Audio

M-Audio Oxygen Series MKV Overview Video

M-Audio

M-Audio Oxygen PRO or Oxygen MKV, which one should you get? | Full Feature Comparison!

GetintheMix

M-Audio Oxygen MKV Overview and USB Connection Setup - Oxygen vs. Oxygen Pro

DSoundman

M-Audio Oxygen MKV Vs. M-Audio Oxygen Pro!

John Mike

M-Audio Oxygen 49 MKV MIDI Keyboard | Gear4music

Gear4music Guitars

M-Audio Oxygen 49 MKV 49 key USB MIDI Keyboard

Kevys RC & Music

Reviews

Add review

PROS

Buttons, knobs, sliders enhance control surface functionality
Quiet, consistent key action with ideal resistance for expression
Solid build quality yet lightweight
Effective with multiple virtual instruments and DAWs
Comes with valuable software bundles
Useful for both beginners and experienced users
Intuitive use, with a sufficient number of keys
Well-supported with online tutorials for easier learning

CONS

Registration and obtaining documentation/software can be frustrating
Learning curve for MIDI programming and feature utilization
QuickStart manual and full user manual are confusing
Trial software offers misleading, limited to short trial periods

Owner Insights

We analyzed real musician discussions from forums and Reddit to find what players love, question, and tweak about M-Audio Oxygen 49 MKV MIDI Keyboard Controller.

Build quality

0 0

It's noted that key contacts may fail over time, turning the controller into a non-functional item without replacement parts.
Source
0 0

The key action is considered acceptable but feels cheap, with some users preferring more resistance in the keys.
Source

Software and compatibility

0 0

Older models may face USB driver issues, potentially limiting their use with newer DAWs unless the DIN out is utilized.
Source
0 0

The MKV model's buttons and their functions differ from both the Pro and MK4 versions, leading to compatibility challenges with DAWs like Cakewalk.
Source
0 0

M-Audio's Preset Editor for the MKV lacks DAW mode, only offering Preset or Global mode, complicating setup compared to other models.
Source
0 0

Some functions like controlling the Master bus are not activated by default on the MKV, requiring additional configuration for full functionality.
Source
0 0

Some users experience MIDI signal dropouts with MacBook Pro, suggesting potential compatibility issues despite the controller working fine on other Macs.
Source

Features and functionality

0 0

Newer mk3 models have synth-action keys that are initially stiff but become more comfortable with use, according to pianists transitioning to MIDI controllers.
Source
0 0

The MKV requires setting the controller to NC2 and selecting Mackie Control in Cakewalk for most functions to work as intended.
Source
0 0

The Oxygen 49 has a one-click transpose function, allowing for easier access to higher or lower octaves without needing a larger keyboard.
Source

Value and pricing

0 0

A used mk3 model at $50 is considered a good deal, but older models are deemed less valuable due to poorer key feel and lack of bundled software.
Source
0 0

Multiple users highlight the controller as offering great value, especially when purchased at discounts around $109.
Source

User experience

0 0

Despite initial setup challenges with Cakewalk, once configured using Mackie Control Universal (Cubase mode), the MKV provides effective control over DAW functions.
Source
0 0

Several owners appreciate the durability of knobs and sliders, describing them as feeling robust and reliable in use.
Source

Use cases and applications

0 0

The Oxygen 49 is praised for its versatility in FL Studio, with users noting that knobs and sliders can be easily assigned to control various elements.
Source

Critic Reviews

M-Audio 49 Oxygen MKV | MusicRadar

musicradar.com

The M-Audio Oxygen 49 MKV is a capable MIDI keyboard that brings a lot to the table with its Chord and Scale modes that enhance songwriting. The Arpeggiator and deep DAW integration are standout features, making it a solid choice for producers. However, the reduced number of pads (only eight instead of sixteen) and some ergonomic challenges compared to its Pro sibling may deter serious users. While it lacks a dedicated MIDI out port, its USB connectivity keeps it relevant for modern setups. Overall, it’s a compelling option for those who prioritize versatility over advanced features.

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Artist usage

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Mindchatter

Music Producer

Verified via Photo

In a video clip shared on Instagram by Mindchatter, the artist can be observed utilizing the M-Audio Oxygen 49 MIDI Keyboard Controller during a live stream, providing clear evidence of the specific musical equipment in use. The post captioned "Next live stream in 1 week 😊 (swipe for full clip)" serves as the source of this information.

Genre Usage

Based on how artists on Equipboard use this gear, it is most commonly found in the following genres.

Used With

Based on how musicians on Equipboard use M-Audio Oxygen 49 MKV MIDI Keyboard Controller, it is most commonly used with the following gear.

HiFiMAN SUNDARA Headphones & In-Ear Monitors

Yamaha CLP-745 Clavinova 88-Key Digital Piano Digital Pianos

ADAM Audio T7V Active & Passive Monitors

Boss RC-505mkII Looper Effects Pedals

Neumann TLM 103 Condenser Microphones

Dangerous Music Monitor ST Remote-Controlled Source & Speaker Switcher Studio Monitor Management

Audient iD44 Audio Interface Audio Interfaces

Apple MacBook Pro (General) Computers & Peripherals

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