M-Audio Oxygen 49 MK4

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$168.62 to $299.00 Price Tier: Budget

4.0 (58)

14 Reviews

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M-Audio Oxygen 49 MKV MIDI Keyboard Controller

$122.00 - $199.00

5.0 (1)

Find out who is using M-Audio Oxygen 49 MK IV

2 community setups

10 wishlisted

110 saved

Page last updated Jul 03, 2026

Pricing and availability

We compare 600+ stores and found this item at 4 stores. Prices updated July 3, 2026.

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3.5 (13)

$179.00

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4.5 (1315)

Used

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4.0 (5)

$168.62 2 available New

$50.00 4 available Used

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3.0 (3)

$179.00

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Average Price: $175

Budget/Beginner

$200

$501+

Price Tier

In the MIDI Keyboard Controllers category, M-Audio Oxygen 49 MK4 is priced in the Budget/Beginner range. This is great gear to get started with or for creators on a budget.

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Price History

Based on price data from 1 merchant for "M-Audio Oxygen 49 MK4". Prices shown reflect NEW condition. Tracking began Apr 2, 2026.

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Description

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Unlock limitless creativity with the M-Audio Oxygen 49 MK4, your portable gateway to the world of music production. This MIDI keyboard controller is not just an update, it's a revolution in intuitive design and seamless integration. Whether you're laying down bass lines or crafting complex melodies, the 49 full-size, velocity-sensitive keys provide a responsive and dynamic playing experience that musicians crave.

Diving deeper into your soundscape, the Oxygen 49 MK4 boasts an array of customizable controls. With eight velocity-sensitive pads, you can effortlessly trigger samples or engage in finger drumming, while the eight assignable knobs and nine faders offer precise manipulation of virtual instruments and plugins. Say goodbye to cumbersome setups—this controller automates the mapping process with your favorite DAWs like Ableton Live, Pro Tools, and Logic, allowing for immediate immersion into your creative process.

Transport controls and track navigation buttons make controlling your digital audio workstation a breeze, keeping your workflow uninterrupted and your focus on the music. The included Ableton Live Lite software and SONiVOX Twist synth bundle transform your desktop into a full-fledged music studio from the moment you unbox.

Key Features:

49 full-size, synth-action velocity-sensitive keys
8 velocity-sensitive trigger pads for versatile beat making
8 assignable knobs for effect and instrument control
9 assignable faders for seamless mixing
Integrated transport controls for DAW management
Automaps with top DAWs: Ableton Live, Pro Tools, Logic, Cubase, and more
LCD screen for real-time parameter feedback
USB-powered and plug-and-play support with USB-MIDI connectivity
Sustain pedal input for expressive performance
Includes Ableton Live Lite for instant music production
Bundled with SONiVOX Twist spectral morphing synthesizer

Videos

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Adventures in Creative Software

How to Program Your M-Audio Oxygen (Mk IV) Midi Controller

Adventures in Creative Software

Feel + Functionality! |M-Audio Oxygen 49 MKIV Midi Controller Review!|

John Mike

M Audio Oxygen 49 Key USB MIDI Controller Keyboard - M Audio Oxygen

American Musical Supply

M-Audio Oxygen MKIV Vs M-Audio Oxygen MKV

John Mike

Reviews

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PROS

More keys and better feel than previous models
Smooth and precise pitch and mod wheels
Lightweight and compact design
9 sliders, USB and MIDI jacks for versatility
Ideal for VSTi synths and pianos
Plug and play, no extra power plug required
Useful drum pads for music production
Controls Pro Tools for live and record sessions

CONS

Shipped without charger in some cases
Sliders and knobs can feel cheap and fragile
Not fully compatible with all DAWs, installation issues
Non-motorized faders stay in 'wrong' position upon project load
Keys are velocity-sensitive but have a plastic feel
Larger size than necessary for some setups, requires desk space
Limited use of pads and faders by some users

Owner Insights

We analyzed real musician discussions from forums and Reddit to find what players love, question, and tweak about M-Audio Oxygen 49 MK4.

Features and functionality

0 0

The M-Audio Oxygen 49 MK4 lacks MIDI DIN ports, requiring USB connection and a MIDI host like a computer for operation.
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It features synth-action keys, which differ from the feel of traditional piano keys, lacking the weighted touch.
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0 0

The Oxygen 49 can transmit unintended double Note On messages, which can be diagnosed using MIDI monitoring software like Snoize's MIDI Monitor.
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The M-Audio Oxygen 49 MK4 includes a free copy of iZotope IRIS 2, offering additional sound design capabilities for users.
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Build quality

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The keyboard is noted for its durability, having survived multiple moves without issues.
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Setup and maintenance

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Users suggest acquiring a USB to MIDI DIN converter for controlling external devices, available for about $8 online.
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0 0

Some users experience clashing notes due to the keyboard's setup; changing mode or resetting to factory settings may resolve this.
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Value and pricing

0 0

The M-Audio Oxygen 49 MK4 is priced significantly lower at $101 compared to Novation Launchkey 49 MK3 at $208 and Arturia Keylab Essential 49 at $189, despite similar functionalities.
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Software and compatibility

0 0

While the M-Audio Oxygen 49 MK4 is bundled with iZotope IRIS 2, the Novation Launchkey includes Ableton Live Lite, offering an upgrade discount for Ableton versions.
Source

Use cases and applications

0 0

The M-Audio Oxygen 49 MK4 is recommended for those using FL Studio who are comfortable manually mapping controls, as opposed to seamless integration with Ableton like the Novation Launchkey 49 MK3.
Source

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4.0 out of 5

Based on 14 Reviews and 58 Ratings

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4 star

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namesuppressed

2113

about 7 years ago

Does more than I need, but feels a bit plastic

I chose this because I saw Imogen Heap use it. It does everything I need... almost too much. I never use the pads, and I don't use the faders as much as I expected to - since they're not motorized, they're always in the 'wrong' position when you load a project. The keys are velocity sensitive but not weighted, so it has a plastic feel. If I was buying again, I'd prefer the key feel of the NI Komplete Kontrol A25. The 49 keys has also turned out to be bigger than I need, so I always have to clear my entire desk & move my wireless keyboard & trackpad when plugging it in. But it's affordable, pretty good for playing VSTi synths & pianos, and I have the same MIDI keyboard as Imogen Heap so I can't blame my gear for any lack of productivity & creativity.

Roles:

Composer

Genres:

Electronica Grunge Industrial rock

jhon_shepherd

407

about 11 years ago

M-Audio love

I first purchased an M-Audio Keystation25 back in 2008 and immediately fell in love with it because of the size and functionality. I had no idea that I would end up using that same controller for 5 years, Sometimes under very extreme circumstances. At last the time had finally come to retire it and look for a new controller, Hence this beast, The M-Audio Oxygen49. All I can say is that this controller practically performs every function I need it to. I especially love the fact that the only time I even have to reach for the mouse is to load a VST. Amazing piece of hardware and I imagine it will be sticking around for quite some time.

foggysunday

104

about 8 years ago

Has everything for any situation

Whenever i start a new project or struggle to create new melodies i just plug it in and experiment. Each time has payed off and i have enjoyed my time with it. Problem is that i don't find myself using it ever that often. This puts me in a weir position where, even when i've owned this for a long time, i haven't explored all the possible uses of it. But i guess it's more my problem :P

azfatboy

1255

about 8 years ago

Feature-packed MIDI keyboard

I picked one of these up because it has a lot of features for not a lot of money. There is a slight trade-off in quality. The sliders feel pretty cheap, and the knobs feel a little fragile. But it all works, so if you take care of it, I think it will last a long time.

gaiden

almost 12 years ago

4 Stars

I bought this as my first MIDI controller, and I got mainly because it had a bit of spotlight since it was a major update. Only problem is that FL hasn't updated to include the pads (haven't gotten 11.1 but whatever), but I'm pretty sure it works with Ableton (ships with Live Lite)

juliano_d_horta_beccari

over 8 years ago

Direct Link w Logic have problems...

Great keyboard for moving around, sliders and knobs great for controlling fx and modulation... But I think M-Audio (and AVID) should pay more attention to the relations between their controllers and the DAWs, this should be no installing at all, and Direct Link for me is a total disappointment...

boe

over 10 years ago

Very good keyboard for new producers

This is the first keyboard i have brought to use for my music production and i am very pleased with it, its not clunky to play and has very usefull drum pads in the top right corner