Pricing and availability

We compare 600+ stores and found this item at 10 stores. Prices updated .

Sweetwater
4.5 (6)
$399.99 $339.99 $60.00 · All time low
Guitar Center
4.5 (3)
$399.99
Amazon
4.5 (241)
$339.99 New
$329.99 Used (Like New)
Reverb
$316.71 New
$280.00 Used
Musician's Friend
5.0 (1)
$399.99 $339.99 $60.00 · All time low
B&H
4.8 (5)
$399.99 $339.99 $60.00 · All time low
Thomann
4.8 (25)
$299.00
Gear4Music
£319.00
Vintage King
$399.99 $339.99 $60.00 · All time low

Average Price: $340

Standard/Professional

$150

$501+

Price Tier

Budget

Standard

High-end

Price History

Based on price data from 7 merchants for "Focusrite Scarlett 16i16 Fourth Generation USB Audio Interface". Prices shown reflect NEW condition. Tracking began Apr 2, 2026.

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Description

Experience the pinnacle of audio interface technology with the Focusrite Scarlett 16i16 Fourth Generation USB Audio Interface. Designed for both budding musicians and seasoned audio engineers, this powerhouse offers a seamless blend of high-fidelity sound and versatile connectivity. With RedNet-derived AD/DA converters, the Scarlett 16i16 delivers pristine audio clarity and a staggering 122dB dynamic range, capturing every nuance of your performance.

The advanced mic preamps, equipped with a generous 69dB of gain, ensure your recordings are rich and detailed. Engage the re-engineered Air Mode to infuse your mixes with an airy, harmonic presence reminiscent of classic studio consoles. Whether you're tracking guitars through its hi-Z inputs or utilizing its expansive I/O options for complex setups, the Scarlett 16i16 adapts to your creative needs effortlessly.

Say goodbye to level-setting headaches with intuitive Auto Gain and Clip Safe features, which automatically adjust your input levels to prevent distortion. Monitor your sessions with confidence using the custom-designed headphone amplifier, complete with independent level control for precise mixing.

Whether you're at home or on the go, the Focusrite Control 2 software and mobile app make managing your setup a breeze, offering full control over routing and mixing. Plus, with the included software bundle featuring Pro Tools Artist and Ableton Live Lite, you're armed with all the tools to produce your next hit.

Key Features:

  • 16x16 USB-C audio interface with RedNet-derived AD/DA converters
  • 4th-generation mic preamps with 69dB gain and re-engineered Air Mode
  • Auto Gain and Clip Safe features for optimal level management
  • Custom-designed headphone amplifier with independent level control
  • Hi-Z inputs for guitars and loopback functionality for virtual routing
  • Includes Pro Tools Artist, Ableton Live Lite, and Hitmaker Expansion software bundle

Owner's manual

Focusrite Scarlett 16i16 Fourth Generation USB Audio Interface User Manual

Product specs

Computer Connectivity USB 2.0
Form Factor Desktop
Simultaneous I/O 16 x 16
Number of Preamps 2 x mic, 2 x instrument
Phantom Power Yes
A/D Resolution Up to 24-bit/192kHz
Analog Inputs 2 x XLR-1/4" combo (mic/line), 4 x 1/4"
Analog Outputs 4 x 1/4"
Digital Inputs 1 x Coax (S/PDIF), 1 x Optical
Digital Outputs 1 x Optical, 1 x Coax (S/PDIF)
Headphones 2 x 1/4"
MIDI I/O In/Out
USB 1 x USB-C, 1 x USB-C (power only)
Features Multi-speaker Monitor Groups: 2.1 channel, 5.1 channel surround (Focusrite Control 2)
Software Avid Pro Tools Intro+, Ableton Live Lite, Hitmaker Expansion Bundle
Compatibility Mac, PC, ChromeOS
OS Requirements - Mac macOS 11 or later
OS Requirements - PC Windows 10 or later
Power Supply USB bus powered
Height 2.38"
Width 8.66"
Depth 6.11"
Weight 2.75 lbs.

FAQs

What are the main connectivity options for the Focusrite Scarlett 16i16 4th Gen USB Audio Interface?

The Focusrite Scarlett 16i16 4th Gen offers USB 2.0 connectivity, with 16x16 simultaneous I/O, including analog inputs and outputs, digital I/O via S/PDIF and Optical, and MIDI In/Out.

Is the Focusrite Scarlett 16i16 4th Gen compatible with major DAWs like Ableton Live and Pro Tools?

Yes, the Focusrite Scarlett 16i16 4th Gen is compatible with major DAWs, including Ableton Live and Pro Tools. It also comes bundled with Ableton Live Lite and Avid Pro Tools Intro+.

Does the Focusrite Scarlett 16i16 4th Gen USB Audio Interface require an external power supply?

No, the Focusrite Scarlett 16i16 4th Gen is USB bus powered, meaning it does not require an external power supply.

What is the audio resolution capability of the Focusrite Scarlett 16i16 4th Gen?

The Focusrite Scarlett 16i16 4th Gen supports up to 24-bit/192kHz audio resolution, providing high-fidelity sound for professional recording and production.

Can the Focusrite Scarlett 16i16 4th Gen be used for multi-speaker monitor setups?

Yes, the Focusrite Scarlett 16i16 4th Gen supports multi-speaker monitor groups, including 2.1 and 5.1 channel surround configurations with Focusrite Control 2 software.

Sweetwater Soundcheck

Sweetwater Soundcheck

Focusrite Scarlett 16i16, 18i16 and 18i20 4th Gen Audio Interfaces Overview

Video thumbnail for Focusrite Scarlett 16i16, 18i16 and 18i20 4th Gen Audio Interfaces Overview by Sweetwater Soundcheck

Focusrite Scarlett 16i16, 18i16 and 18i20 4th Gen Audio Interfaces Overview

Sweetwater Soundcheck

Sweetwater Soundcheck

Reviews

PROS

  • High-quality preamps deliver clean, noise-free recordings

  • Durable metal body with smooth, rubbery knobs

  • Independent power supply, not reliant on USB power

  • MIDI connectivity for versatile instrument integration

  • Supports high sampling rates up to 192 kHz

  • User-friendly Focusrite Control software with loopback feature

  • Versatile input/output options, including ADAT and optical

  • Compatible with iPhone/iPad apps for remote control

  • Excellent price-to-performance ratio

  • Easy setup process, even for beginners

CONS

  • Lacks "computer mode" for power management

  • Limited microphone/instrument inputs compared to higher models

  • Physical knobs cannot be controlled via software sliders

  • Absence of speaker "thump" protection for switching devices

Owner Insights

We analyzed real musician discussions from forums and Reddit to find what players love, question, and tweak about Focusrite Scarlett 16i16 Fourth Generation USB Audio Interface.

Software and compatibility

  • The Scarlett 16i16 may cause bluescreens if unplugged while the laptop is powered on, potentially due to its USB bus-powered nature.

    Source

Features and functionality

  • Windows users need to configure Focusrite Control 2 settings to establish the Scarlett as the default playback/recording device.

    Source
  • The 16i16 offers ADAT expansion, allowing for 10 additional input channels, unlike the 8i6 which lacks this capability.

    Source

Comparisons

  • The 16i16's panel controls are available directly on the device, whereas the 8i6 requires software for similar adjustments.

    Source

Use cases and applications

  • Bedroom producers or YouTubers might find the 16i16's dual headphone outputs beneficial for collaborative work or monitoring.

    Source

Value and pricing

  • Some users report finding the 8i6 at significantly lower prices than the 16i16, making it a budget-friendly option without ADAT features.

    Source

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Genre Usage

Based on how artists on Equipboard use this gear, it is most commonly found in the following genres.

Used With

Based on how musicians on Equipboard use Focusrite Scarlett 16i16 Fourth Generation USB Audio Interface, it is most commonly used with the following gear.

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